Testing Home-based Exercise Strategies to Improve Exercise Participation and Cardiovascular Health in Underserved Minority Patients With Cancer Undergoing Chemotherapy: the THRIVE Study

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The purpose of this research is to determine whether a 16 week, home-based, aerobic and resistance exercise intervention will increase physical activity levels in Black and Hispanic breast, colorectal, or prostate cancer patients. The names of the study interventions involved in this study are: * Supervised aerobic and resistance exercise (SUP) - virtually supervised 16- week aerobic and resistance exercise performed at home via Zoom. * Unsupervised aerobic and resistance exercise (UNSUP) - home-based 16- week aerobic and resistance exercise. * Attention control (AC) - 16-week home-based stretching.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Over 18 years old; children under the age of 18 will be excluded due to rarity of disease

• Newly diagnosed with stage I-III breast, colorectal or prostate cancer

• Self-identify as Hispanic or Black

• Are within 4 weeks of initiating chemotherapy

• Overweight or obese (BMI \>25kg/m2 or body fat percent \>30)

• Physician's clearance to participate in moderate-vigorous intensity exercise

• Speak English or Spanish

• Engaging in less than 90 minutes of moderate-or-vigorous physical activity per week

• Willing to travel to Dana-Farber Cancer Institute for necessary data collection

• Ability to understand and the willingness to sign a written informed consent document.

Locations
United States
Massachusetts
Brigham and Women's Hospital
RECRUITING
Boston
Dana Farber Cancer Institute
RECRUITING
Boston
Contact Information
Primary
Christina Dieli-Conwright, PhD, MPH
ChristinaM_Dieli-Conwright@dfci.harvard.edu
617-582-8321
Backup
Mary Norris, MSc
maryk_norris@dfci.harvard.edu
8572150195
Time Frame
Start Date: 2022-10-31
Estimated Completion Date: 2026-05-31
Participants
Target number of participants: 135
Treatments
Experimental: Supervised aerobic and resistance exercise (SUP)
Participants will be randomly assigned to receive 3x weekly at home, virtually supervised aerobic and resistance exercise sessions with a certified exercise trainer for 16 weeks.~Participants will also have a baseline test, mid intervention cardiovascular and strength tests and one postintervention and one follow up visit.
Experimental: Unsupervised aerobic and resistance exercise (UNSUP)
Participants will be randomly assigned to receive 3x weekly at home, unsupervised aerobic and resistance exercise sessions with a 1x weekly telehealth call with a certified exercise trainer for 16 weeks.~Participants will also have a baseline test, mid intervention cardiovascular and strength tests and one postintervention and one follow up visit.
Active_comparator: Attention Control (AC)
Participants will be randomly assigned to receive 3x weekly at home stretching exercise for 16 weeks.~Participants will also have a baseline test, mid intervention cardiovascular and strength tests and one postintervention and one follow up visit.
Sponsors
Collaborators: University of Massachusetts, Boston, National Cancer Institute (NCI)
Leads: Dana-Farber Cancer Institute

This content was sourced from clinicaltrials.gov